SIMEPREVIR RESTORES THE ANTI-STAPHYLOCOCCUS ACTIVITY OF POLYMYXINS

Simeprevir restores the anti-Staphylococcus activity of polymyxins

Abstract Methicillin-resistant Staphylococcus aureus (MRSA) infection poses a severe threat to global public health due to its high mortality.Currently, polymyxins are mainly used for the treatment of Gram-negative bacterial-related infection, while exhibiting limited Automotive antibacterial activities against Staphylococcus aureus (S.aureus).Howe

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Intraoperative fluorescence imaging with aminolevulinic acid detects grossly occult breast cancer: a phase II randomized controlled trial

Abstract Background Re-excision due to positive margins following breast-conserving surgery (BCS) negatively affects patient outcomes and healthcare costs.The inability to visualize margin involvement is a significant challenge in BCS.5-Aminolevulinic acid hydrochloride (5-ALA HCl), a non-fluorescent oral prodrug, causes intracellular accumulation

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